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Abstract #4335

The Application of T2 Star Weighted Angiography (SWAN) in Hypoxic-Ischemic Encephalopathy

Zhengrong Xia1, Yuhua Li1, He Wang2

1Department of Radiology, Xinhua Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai, China, People's Republic of; 2Global Applied Science LaboratoryGlobal Applied Science Laboratory, GE Healthcare

The value of T2 Star Weighted Angiography(SWAN) in hypoxic-ischemic encephalopathy(HIE) was investigated. 105 neonates who suspected HIE underwent MR scanning on a GE HDx twin speed 3.0T MR scanner. All of these patients were evaluated with SWAN in addition to other conventional MRI techniques, including FLAIR, FSE, DWI. SWAN had higher sensitivity than other sequences for the detection of germinal matrix hemorrhage, intraventricular hemorrhage, which is a strong predictor for long-term neurologic and neuropsychologic outcomes. Furthermore, SWAN demonstrated that the lesions in preventricular white matter rarely contain hemorrhage. SWAN is recommended to become a part of routine HIE MRI protocols.