Jin Tang1, Saifeng Liu1, Jaladhar Neelavalli2, E. Mark Haacke2,3
1School of Biomedical Engineering, McMaster University, Hamilton, Ontario, Canada; 2The MRI Institute for Biomedical Research, Detroit, MI, United States; 3Academic Radiology, Wayne State University, Detroit, MI, United States
Mapping susceptibility from field perturbation data is a difficult inverse problem. Here we present a unique k-space iteration/image processing approach which dramatically reduced reconstruction streak artefacts caused by an ill-posed problem of inverse filter and simultaneously improved the accuracy of susceptibility quantification. This method could potentially be used for quantitative in vivo venous oxygen saturation measurement using SWI data.