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Abstract #4482

Simulation of Double Pulsed Field Gradient Experiments

Gregory T. Baxter1, Evren Ozarslan2,3, Peter J. Basser2, Lawrence R. Frank1,4

1Radiology, UCSD, La Jolla, CA, United States; 2STBB / PPITS / NICHD, National Institutes of Health, Bethesda, MD, United States; 3Center for Neuroscience & Regenerative Medicine, USUHS, Bethesda, MD, United States; 4VASDHS, La Jolla, CA, United States

Double pulsed field gradient (DPFG) MR experiments are growing in popularity owing to their ability to reveal new structural features of tissue. Here, we simulate DPFG experiments in restricted environments and compare these results against theory. We then simulate diffusion in arrays of microcapillaries both filled and surrounded by water. We find significant changes in the MR signal as a function of cylinder spacing.