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Abstract #4516

Orientation & Microstructure Effects on Susceptibility Reconstruction: A Diffusion Phantom Study

Johannes Lindemeyer1, Ana-Maria Oros-Peusquens1, Ezequiel Farrher1, Farida Grinberg1, Nadim Jon Shah1,2

1Institute of Neuroscience & Medicine - 4, Forschungszentrum Juelich, Juelich, Germany; 2Department of Neurology, Faculty of Medicine, JARA, RWTH Aachen, Aachen, Germany

The influence of parallel fibre structures on the static field and on the observed susceptibility are investigated using a diffusion phantom. A series of measurements at various orientations with respect to B0 and comparative simulations are presented. A bulk-susceptibility appears to be insufficient to represent a parallel fibre area. A simple chequerboard fibre-stacking simulation allowed us to produce good correspondence with observed field shifts.