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Abstract #4646

Contrast Agents & MR Protocols for Molecular Imaging of Murine Myocardial Infarction

Leonie Elisabeth Paulis1, Bram Franciscus Coolen1, Tessa Geelen1, Klaas Nicolay1, Gustav Jacobus Strijkers1

1Biomedical NMR, Biomedical Engineering, Eindhoven University of Technology, Eindhoven, Netherlands

Recently, major progress has been made in the field of molecular MRI of mouse myocardial infarction. Contrast agents have been designed and successfully applied to image cell death, inflammation and LV remodeling. To visualize these contrast agents, dedicated MRI sequences are required. Specifically, T1- and T2-weighted sequences have been optimized, quantitative T1 and T2 mapping protocols have been developed and first-pass perfusion measurements have been implemented.