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Abstract #0084

Myocardial T1 Mapping with Phase-Sensitive Motion Correction & Inversion Recovery Fitting

Hui Xue1, Andreas Greiser2, Christoph Guetter1, Sven Zuehlsdorff3, Marie-Pierre Jolly1, Andrew E. Arai4, Jens Guehring2, Peter Kellman4

1Siemens Corporate Research, Princeton, NJ, United States; 2Imaging & IT Division, Siemens AG, Healthcare Sector, Erlangen, Germany; 3CMR R&D, Siemens Medical Solutions USA, Inc., Chicago, IL, United States; 4Laboratory of Cardiac Energetics, National Institutes of Health, National Heart, Lung and Blood Institute, Bethesda, MD, United States

The image quality of myocardial T1 mapping using the modified Look-Locker Inversion Recovery (MOLLI) sequence is often degraded by the motion among sampled images. A fully automated motion correction directly utilizing MOLLI images is highly challenging due to significantly varying image contrast and the signal inversion. To overcome this difficulty, we propose to restore the signal polarity for the entire MOLLI series using the phase sensitive image reconstruction. The inversion recovery fitting on MOLLI signals with restored polarity is more efficient and leads to lower residual errors. in vivo evaluation was performed on a cohort of 17 patients.