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Abstract #0101

Intracranial Compliance Study by Phase Contrast Magnetic Resonance Imaging in Newborns & Children

Cyrille Capel1, Catherine Gondry-Jouet2, Bndicte Krejpowicz3, Vronique Courtois3, Malek Makki4, Roger Bouzerar1, Olivier Baledent1

1Image Processing Unit, University Hospital, Amiens, France; 2Radiology, University Hospital, Amiens, France; 3Ecole suprieure d'ostopathie et de biomcanique, Ostobio, Paris, France; 4MRI Research Center, University Chidlren Hospital, Zurich, Switzerland

We applied 2D cine-PC MRI to investigate the intracranial compliance of 29 healthy term neonates and children. Cerebral blood volume expansion, during cardiac cycle, was calculated from internal carotid and vertebral arteries and jugular veins' flows. The cerebrospinal fluid volume flushing out of the cranium owing to intracranial pressure increase was measured at the cervical level. An index of intracranial compliance, defined as the ratio of blood and CSF volume changes during the cardiac cycle, was calculated. We have demonstrated that intracranial compliance variations during the first months of life could be studied using PCMRI