Robert Frost1, David A. Porter2, Gwenaelle Douaud1, Peter Jezzard1, Karla L. Miller1
1FMRIB Centre, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, United Kingdom; 2Healthcare Sector, Siemens AG, Erlangen, Germany
Readout-segmented EPI (rs-EPI) for diffusion imaging reduces distortion and T2* blurring and enables higher resolution relative to single-shot EPI (ss-EPI). However, the long scan times caused by segmenting the acquisition of k-space limit the number of slices and/or diffusion directions. A blipped-CAIPI multiband modification to rs-EPI has the potential to address the scan time issue and is demonstrated here with slice acceleration factor two. Trace-weighted images with 0.9x0.9x4mm resolution acquired in clinically relevant scan times are presented. Diffusion tractography is compared from data acquired at 2 and 1.5mm isotropic resolution for rs- and ss-EPI.