Xia Liang1, 2, Qihong Zou3, Yong He2, Yihong Yang4
1Neuroimaging Research Branch,, National Institute on Drug Abuse, National Institutes of Health, Baltimore, MD, United States; 2State Key Laboratory of Cognitive Neuroscience, Beijing Normal University, Beijing, China; 3MRI Research Center and Beijing City Key Lab for Medical Physics and Engineering, Peking University, Beijing, China; 4Neuroimaging Research Branch, National Institute on Drug Abuse, National Institutes of Health, Baltimore, MD, United States
We investigated the relationship between functional connectivity strength and cerebral blood flow (CBF) by analyzing a set of resting-state functional BOLD and ASL imaging data collected on the same subjects to test the hypothesis that brain regions with stronger functional connectivity demand more metabolic supply. Our results show that functional connectivity and CBF are highly correlated across voxels as well as across subjects.
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