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Abstract #0243

The Comparison of Arterial Spin Labeling Perfusion MRI & DCE-MRI in Patients with Prostate Cancer

Wenchao Cai1, Feiyu Li1, Jing Wang2, Jue Zhang2, 3, Xiaoying Wang1, 2, Xuexiang Jiang1

1Department of Radiology, Peking University First Hospital, Beijing, China; 2Academy for Advanced Interdisciplinary Studies, Peking University, Beijing, China; 3College of Engineering, Peking University, Beijing, China

Introduction:Arterial spin labeling (ASL) MRI has the advantage of no administration of the extrinsic tracer which are capable of absolutely quantitatively measuring the microvascular perfusion characteristics of tissue. Purpose: To explore the correlation between the BF from ASL and kinetic parameters from DCE-MRI in patients with prostate cancer.Methods: Six patients with pathologically confirmed prostate cancer were recruited in this study to take the PASL pulse sequence and DCE MR examinations. Results:Significant positive correlations between BF value and Ktrans, Kep were observed in all four TI (p < 0.05, Spearmans correlation analysis). However, no significant correlation between BF and Ve was found. Conclusion:The arterial spin labeling sequence with no contrast medium allows extraction of blood flow information specific to the angiogenic process of prostate.