Abstract #0252

Diffusion Tractography in Term Neonates with Hypoxic-Ischemic Encephalopathy: Projection Fiber System & Corpus Callosum Involvement as Predictors of Neurodevelopmental Outcome

Katyucia de Macedo Rodrigues¹, Maria de Carmen Fons Stupina²,³, Ainsley MacLean⁴, Janet Soul², Rudolph Pienaar⁵, Omar Khwaja², P. Ellen Grant⁵

¹Radiology, Children's Hospital Boston, Boston, Massachusettes, United States; ²Neurology, Children's Hospital Boston, Boston, Massachusettes, United States; ³Pediatric Neurology, Sant Joan de Seu Hospital for Children, Barcelona, Spain; ⁴Neuroradiology, Brigham and Women's Hospital, Boston, Massachusettes, United States; ⁵Center for Fetal-Neonatal Neuroimaging & Developmental Science, Children's Hospital Boston, Boston, Massachusettes, United States

We performed a tractography-based DTI analysis of projection and comissural tracts in term/near term neonates who presented perinatal HIE and had a brain MRI performed within 7 postnatal days and neonates with normal MRI without HIE and studied its correlation with early motor outcome.