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Abstract #0291

Resolution-Related Diffusion Damping in Fast Spin Echo Sequences

Oliver Bieri1, Carl Ganter2, Klaus Scheffler3, 4

1Division of Radiological Physics, Department of Radiology and Nuclear Medicine, University of Basel Hospital, Basel, Switzerland; 2Department of Radiology, Klinikum rechts der Isar, Technische Universitt Mnchen, Munich, Germany; 3High-Field Magnetic Resonance Center, Max Planck Institute for Biological Cybernetics, Tbingen, Germany; 4Department of Neuroimaging and MR-Physics, Centre for Integrative Neuroscience, University of Tbingen, Tbingen, Germany

We have recently shown that the tissue-fluid contrast of nonbalanced steady state free precession (SSFP) shows an unexpected strong sensitivity on resolution: an increase in the spatial resolution goes with an increase in spoiling moments leading to a pronounced diffusion damping of fluids. Clearly, this effect is not confined to SSFP, but can affect the contrast of other multi-pulse sequences that show resolution dependent spoiling moments, such as RARE (TSE, FSE). In this work, we will show that RARE sequences show a similar fluid-tissue contrast modulation as nonbalanced SSFP.