Philip M. Robson1, Claudia Calcagno1, Sarayu Ramachandran1, Venkatesh Mani1, Melanie Kotys-Traughber2, Zahi A. Fayad1
1Translational and Molecular Imaging Institute, Mount Sinai School of Medicine, New York, NY, United States; 2Philips Healthcare, Cleveland, OH, United States
A new sequence interleaving bright-blood GRE full-image and dark-blood SE image-segment acquisitions is investigated for application to quantitative Dynamic Contrast Enhanced imaging of the carotid arteries in atherosclerosis. Bright-blood images are acquired with 1-sec temporal and low 0.5x4-mm spatial resolutions to capture the arterial input function, while the interleaved dark-blood images have lower temporal and 0.5x0.5-mm spatial resolution to image the thin vessel wall without blooming of the bright vessel lumen. This study in three subjects demonstrates the feasibility of simultaneously-acquired combined image contrasts. Contrast agent kinetic parameters measured in the vessel wall are consistent with those in the literature.