Pathological Tissue Classification by Multiparametric MRI: Technical Development & Application in Renal Masses Characterisation.

Rado Andriantsimiavona¹, Dow-Mu Koh¹, David Collins¹, Simon Doran¹, Martin Leach¹

We have developed an interactive framework that allows spatially synchronised 3D visualisation and analysis of anatomical, diffusion-weighted and dynamic contrast enhanced MR data in multi-planar orientations and used it to establish correlations between parametric maps derived from MRI (ADC and AUC) and the corresponding characteristics measured from paired histological sections. Our aim is to provide biologically meaningful interpretations of multiparametric analysis as well as build a computer aided tissue classification scheme for the RCC model.