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Abstract #0387

Local Maxwell Tomography Using Transmit-Receive Coil Arrays for Contact-Free Mapping of Tissue Electrical Properties & Determination of Absolute RF Phase

Daniel K. Sodickson1, 2, Leeor Alon1, 2, Cem Murat Deniz1, 2, Ryan Brown1, Bei Zhang1, Graham C. Wiggins1, Gene Y. Cho1, 2, Noam Ben Eliezer1, Dmitry S. Novikov1, Riccardo Lattanzi1, 2, Qi Duan3, Lester A. Sodickson4, Yudong Zhu1, 2

1Bernard and Irene Schwartz Center for Biomedical Imaging, Department of Radiology, New York University School of Medicine, New York, NY, United States; 2Sackler Institute of Graduate Biomedical Sciences, New York University School of Medicine, New York, NY, United States; 3National Institutes of Health, Bethesda, MD, United States; 4Cambridge Research Associates, Newton, MA, United States

We introduce a new general approach to mapping the electrical properties of tissue or materials. Unlike prior MR-based techniques, Local Maxwell Tomography (LMT) is free of assumptions regarding RF phase and coil/field/magnetization structure. LMT solves simultaneously for key functions of the absolute RF phase distribution along with unknown permittivity and conductivity, using complementary information from the transmit and receive sensitivity distributions of multiple coils to resolve ambiguities. LMT, from which EPT may be derived as a special case, can operate at arbitrary field strength, with a wide range of coil designs, and free of errors associated with rapid field variation.