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Abstract #0408

Quantitative Susceptibility Mapping (QSM) of Intracranial Calcification: Comparison with Gradient Echo (GRE) Phase Images and CT

Weiwei Chen1, Tian Liu2, Shuai Wang3, Wenzhen Zhu1, Yi Wang4, 5

1Radiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science&Technology, Wuhan, Hubei, China; 2MedImageMetric LLC, New York, NY, United States; 3University of Electronic Science and Technology of China, Chengdu, Sichuan, China; 4Radiology, Weill Cornell Medical College, New York, NY, United States; 5Biomedical Engineering, Cornell University, Ithaca, NY, United States

38 consecutive patients with suspected pathological intracranial calcifications were imaged with both gradient echo (GRE) MRI and CT. Both GRE phase and quantitative susceptibility mapping (QSM) reconstructed from GRE data were analyzed for detecting calcifications using CT as the reference standard. Our data demonstrated that GRE phase images have poor accuracy, while QSM has a fair good accuracy.