Abstract #0480

Fibrin Targeted MRI Allows Staging of Deep Venous Thrombosis and Identifies Thrombi Amenable for Thrombolysis

Marcelo E. Andia¹, Prakash Saha², Steven Grover², Andrea J. Wiethoff¹, Tobias Schaeffter¹, Alberto Smith², Rene M. Botnar¹

¹Division of Imaging Sciences and Biomedical Engineering, Kings College London, London, United Kingdom; ²Academic Department of Surgery, Cardiovascular Division, Kings College London, London, United Kingdom

The in vivo evaluation of the stage of organization of venous thrombosis could help guiding medical treatment and intervention. In this work we show that the use of EP-2104R, a fibrin specific contrast agent, provides valuable information on the stage of thrombus organization and allows identification of thrombus suitable for lysis.