Abstract #0543

Design & Evaluation of an Eight Channel TX/RX Hybrid Applicator for Imaging & Targeted RF-Heating at 7.0 T

Lukas Winter¹, Celal zerdem¹, Werner Hoffmann², Helmar Waiczies¹, Davide Santoro¹, Alexander Mller¹, Tomasz Lindel¹, Wolfgang Renz¹,³, Conrad Martin¹, Frank Seifert², Bernd Ittermann², Thoralf Niendorf¹,⁴

¹Berlin Ultrahigh Field Facility (B.U.F.F.), Max-Delbrueck-Center for Molecular Medicine, Berlin, Germany; ²Physikalisch Technische Bundesanstalt (PTB), Berlin, Germany; ³Siemens Healthcare, Erlangen, Germany; ⁴Experimental and Clinical Research Center (ECRC), Charit - University Medicine Campus Berlin Buch, Berlin, Germany

Combining RF hyperthermia and MR imaging is conceptually appealing to pursue spatially and temporally controlled and monitored RF heating. The benefits of this approach could be used as an adjunctive therapy for established cancer treatments including radiotherapy and chemotherapy , targeted drug delivery and targeted MR contrast agent delivery. This study demonstrates the feasibility of an 8 channel TX/RX hybrid applicator tailored for imaging and targeted hyperthermia at 7.0T