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Abstract #0543

Design & Evaluation of an Eight Channel TX/RX Hybrid Applicator for Imaging & Targeted RF-Heating at 7.0 T

MAGNA25Lukas Winter1, Celal zerdem1, Werner Hoffmann2, Helmar Waiczies1, Davide Santoro1, Alexander Mller1, Tomasz Lindel1, Wolfgang Renz1, 3, Conrad Martin1, Frank Seifert2, Bernd Ittermann2, Thoralf Niendorf1, 4

1Berlin Ultrahigh Field Facility (B.U.F.F.), Max-Delbrueck-Center for Molecular Medicine, Berlin, Germany; 2Physikalisch Technische Bundesanstalt (PTB), Berlin, Germany; 3Siemens Healthcare, Erlangen, Germany; 4Experimental and Clinical Research Center (ECRC), Charit - University Medicine Campus Berlin Buch, Berlin, Germany

Combining RF hyperthermia and MR imaging is conceptually appealing to pursue spatially and temporally controlled and monitored RF heating. The benefits of this approach could be used as an adjunctive therapy for established cancer treatments including radiotherapy and chemotherapy , targeted drug delivery and targeted MR contrast agent delivery. This study demonstrates the feasibility of an 8 channel TX/RX hybrid applicator tailored for imaging and targeted hyperthermia at 7.0T