Abstract #0549

Diffusion Tensor Magnetic Resonance Tractography of the Prostate: Feasibility for Mapping Neurovascular Anatomy

Daniel Jason Aaron Margolis¹, Benjamin Ellingson², Shyam Natarajan³, Robert Reiter⁴, Taryar Zaw¹, Peter Schulam⁴, Steven Raman¹, David Finley⁵

¹Department of Radiology, UCLA David Geffen School of Medicine, Los Angeles, CA, United States; ²Department of Radioloyg, UCLA David Geffen School of Medicine; ³Department of Bioengineering, UCLA David Geffen School of Medicine, Los Angeles, CA, United States; ⁴Department of Urology, UCLA David Geffen School of Medicine; ⁵Department of Urology, Kaiser Permanente Los Angeles

Eight men scheduled to prostatectomy underwent endorectal multiparametric magnetic resonance imaging (MRI) of the prostate with DTI. DTI tractography was successfully performed in all eight patients, visualizing fiber tracts around the prostate. DTI tractography of the prostate effectively visualized periprostatic fiber tract anatomy. Variation in tract distribution existed within individual patients and between patients. Some patients had disproportionately tract mass from one side of the prostate to the other. These findings have potential applicability for the generation of patient-specific pre-operative nerve sparing plans for RP and for the quantitative evaluation of potency outcomes.