Abstract #0566

Diffusion Properties of Uterine Fibroids Pre- & Post- Uterine Fibroid Embolization

Jennifer W. Chong¹, Natalie Yang², Sarah J. Jenkins³, Errol Colak¹, Shalini Anthwal¹, Andrew A. Common¹, Vikram Prabhudesai¹, Anish Kirpalani¹

¹Department of Medical Imaging, University of Toronto, St. Michael's Hospital, Toronto, ON, Canada; ²Department of Radiology, Austin Health, Heidelberg, Australia; ³Department of Diagnostic Imaging, Memorial University, St. John's, NL, Canada

A decrease in uterine fibroid enhancement on pelvic MRI is routinely used to monitor patients' response to uterine fibroid embolization (UFE). In this prospective cohort study of 50 patients (88 uterine fibroids), we examined whether the ADC from diffusion-weighted MRI also changed post-UFE. We found a statistically significant rise in the mean ADC of fibroids post-UFE. We also found that fibroids which have more residual contrast enhancement post-UFE had a higher pre-UFE ADC. ADC may therefore have a clinically important role in predicting treatment response.