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Abstract #0615

Cerebrospinal Fluid (CSF) Flow Suppressed Spinal Cord Functional MRI Using Multi-Slice DANTE-EPI

MAGNA25Linqing Li1, Yazhuo Kong1, Jonathan Brooks1, Karla Miller1, Peter Jezzard1

1FMRIB, Clinical Neurology Department, University of Oxford, Oxford, United Kingdom

DANTE pulse trains (a rapid series of low flip angle RF pulses interspersed with gradients) can attenuate moving CSF signal and preserve most of the static tissue signal. Here, we propose a method that employs DANTE preparation for CSF flow suppression in multi-slice spinal cord fMRI. Compared to a conventional EPI spinal cord sequence, the temporal variance within the spinal cord was decreased. Improved activation patterns were observed using a block-design finger tapping task.