Abstract #0626

Oxygen-Enhanced MRI Vs. Quantitative CT Vs. Perfusion SPECT/CT: Quantitative and Qualitative Capability to Predict Therapeutic Effect for Lung Volume Reduction Surgery Candidates

Yoshiharu Ohno¹,², Mizuho Nishio¹, Hisanobu Koyama¹,², Takeshi Yoshikawa¹, Sumiaki Matsumoto¹, Daisuke Takenaka¹, Katsusuke Kyotani², Nobukazu Aoyama², Hideaki Kawamitsu², Makoto Obara³, Marc van Cauteren⁴, Kazuro Sugimura¹

¹Radiology, Kobe University Graduate School of Medicine, Kobe, Hyogo, Japan; ²Radiology, Kobe University Hospital, Kobe, Hyogo, Japan; ³Philips Electronics Japan, Tokyo, Japan; ⁴Philips Healthcare Asia Pacific, Tokyo, Japan

O2-enhanced MRI can assess regional ventilation and alveolocapillary gas transfer of molecular oxygen. However, none of these studies have examined the quantitative and qualitative capabilities of O2-enhanced MRI for evaluation of candidates for lung volume reduction surgery (LVRS), and compared with that of evaluation by means of thin-section MDCT and perfusion SPECT/CT. The purpose of the study was thus to prospectively and directly compare the quantitative and qualitative capabilities of O2-enhanced MRI, thin-section MDCT and perfusion SPECT/CT to predict therapeutic outcomes for LVRS candidates.