Abstract #0762

Application of a Three-Dimensional Phase-Contrast MR Sequence to Determine Blood Flow Pattern Within Brain Aneurysms

Myriam Edjlali¹, Pauline Roca¹, Ccile Rabrait², Kevin M. Johnson³, Oliver Wieben³,⁴, Denis Trystram¹, Olivier Naggara¹, Jean-Franois Meder¹, Catherine Oppenheim¹

¹Department of Neuroradiology, Sainte-Anne Hospital, University of Paris Descartes, UMR S894, Paris, France; ²GE Healthcare, Vlizy, France; ³Department of Medical Physics, University of Wisconsin, Madison, WI, United States; ⁴Department of Radiology, University of Wisconsin, Madison, WI, United States

We present the first application of a three-dimensional phase-contrast MR sequence (PC VIPR) for the study of flow pattern within human brain aneurysms (n=14, diameter 4-24 mm) and its comparison to Digital Subtraction Angiography (DSA). High spatial resolution (0.85 mm3) PC VIPR velocity maps were informative for all patients, allowing blood flow tracking within all aneurysms. PC VIPR blood flow patterns were consistent with DSA patterns when informative (n=7/14). This new insight in flow tracking allowed us to distinguish in-vivo and non-invasively three flow patterns: a recirculation pattern (n=8), a direct inflow jet (n=1), and a lateral flow pattern (n=5).