Myriam Edjlali1, Pauline Roca1, Ccile Rabrait2, Kevin M. Johnson3, Oliver Wieben3, 4, Denis Trystram1, Olivier Naggara1, Jean-Franois Meder1, Catherine Oppenheim1
1Department of Neuroradiology, Sainte-Anne Hospital, University of Paris Descartes, UMR S894, Paris, France; 2GE Healthcare, Vlizy, France; 3Department of Medical Physics, University of Wisconsin, Madison, WI, United States; 4Department of Radiology, University of Wisconsin, Madison, WI, United States
We present the first application of a three-dimensional phase-contrast MR sequence (PC VIPR) for the study of flow pattern within human brain aneurysms (n=14, diameter 4-24 mm) and its comparison to Digital Subtraction Angiography (DSA). High spatial resolution (0.85 mm3) PC VIPR velocity maps were informative for all patients, allowing blood flow tracking within all aneurysms. PC VIPR blood flow patterns were consistent with DSA patterns when informative (n=7/14). This new insight in flow tracking allowed us to distinguish in-vivo and non-invasively three flow patterns: a recirculation pattern (n=8), a direct inflow jet (n=1), and a lateral flow pattern (n=5).