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Abstract #0838

Spinal Cord MR Spectroscopy in Neoplastic Lesions

Andreas Hock1, Fuchs Alexander1, Peter Boesiger1, Anke Henning1, Spyros S. Kollias2

1University and ETH Zurich, Institute for Biomedical Engineering, Zurich, Switzerland; 2Institute of Neuroradiology, University Hospital of Zurich, Zurich, Switzerland

Single voxel 1H magnetic resonance spectroscopy (MRS) provides information about biochemical processes of neuronal tissue which is complementary to conventional MRI examinations and is therefore a promising tool for investigation of various spinal cord pathologies. In this work, a protocol for spinal cord MRS allowing robust and high quality spinal cord acquisitions was developed. The results show specific changes in the metabolite fingerprint of tumor patients compared to controls and patients suffering from multiple sclerosis.