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Abstract #0850

Correlation of MRI-OEF & PET-OEF Neuroimaging Data for Study of Hypoxia in Brain Tumors

Parinaz Massoumzadeh1, Hongyu An2, Joshua Shimony1, Dhanashree Rajderkar1, Anna Carlson1, Jon Christensen1, Zhang Xiaodong2, Daniel Marcus1, Keith Rich3, Tammie Benzinger1

1Mallinckrodt Institute of Radiology, Washington University in St. Louis, School of Medicine, St. Louis, MO, United States; 2Department of Radiology, University of North Carolina, School of Medicine, Chapel Hill, NC, United States; 3Neurosurgery, Washington University in St. Louis, School of Medicine, St. Louis, MO, United States


Cerebral hypoxia can potentially impact treatment outcome and brain tumor patient survival. Preliminary results of a non-contrast MR procedure for measuring brain and brain tumoral OEF are presented and compared with the results obtain using the noninvasive 15O-PET technique. Although good correlation between OEF-MR and OEF-PET is obtained, and both method show abnormality in tumor area, some discrepancy between the two methods is observed which requires further investigation.