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Abstract #0872

Quantitative MR Imaging of Brain Tumors: A Step Forward?

Dita Wagnerova1, Vit Herynek1, Alberto Malucelli2, Monika Dezortova1, Josef Vymazal3, Dusan Urgosik4, Martin Syrucek5, Filip Jiru1, Antonin Skoch1, 6, Robert Bartos2, Martin Sames2, Milan Hajek1

1Department of Diagnostic and Interventional Radiology, Institute for Clinical and Experimental Medicine, Prague, Czech Republic; 2Department of Neurosurgery, JE Purkyne University and Masaryk Hospital, Usti nad Labem, Czech Republic; 3Department of Radiology, Na Homolce Hospital, Prague, Czech Republic; 4Stereotactic and radiation neurosurgery, Na Homolce Hospital, Prague, Czech Republic; 5Department of Pathology, Na Homolce Hospital, Prague, Czech Republic; 6International Clinical Research Center, St. Anne's University Hospital Brno, Brno, Czech Republic

The specific correlation patterns between metabolic values, mean diffusivity and T2 relaxation times based on multivoxel analysis were observed for low and high grade gliomas, lymphomas, recurrent lesions and tissue changes by radiation/chemotherapy which enable not only tissue differentiation (healthy tissue, edema, tumor infiltrated edema, tumor; tumor recurrence vs. radiation necrosis), but also tumor type differentiation. Combination of several MR methods can be used for quantitative description of tumors to improve the outcome from MR examination of patients.