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Abstract #0940

Time-Course & High-Resolution MRI in Developing Primate Brain of Common Marmoset

Keigo Hikishima1, 2, Kazuhiko Sawada3, Yuji Komaki1, 2, Ayako Murayama2, Kenji Kawai1, Nanako Sato1, Takashi Inoue1, Toshio Ito1, Suketaka Momoshima4, Hirotaka James Okano5, Erika Sasaki1, Hideyuki Okano2

1Central Institute for Experimental Animals, Kawasaki, Kanagawa, Japan; 2Department of Physiology, Keio University School of Medicine, Shinjuku, Tokyo, Japan; 3Tsukuba International University; 4Department of Radiology, Keio University School of Medicine; 5Division of Regenerative Medicine, Jikei University School of Medicine

The common marmoset, a small New World primate species, has been widely used in neuroscience research. It is essential to evaluate and characterize the brain organization during pre- and post-natal development non-invasively. However, little is known about either brain morphology or even imaging techniques. We reported time-course and high-resolution MRI of the developing brain in the marmoset and advanced visualization in the changes of cortical thickness and fiber structure of commissure bundles using diffusion tensor imaging.