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Abstract #0999

Measurement of Metabolites Longitudinal (T1) & Transverse (T2) Values for Absolute Quantification by 1H-MRS in Aging Brain at 3Tesla

Pui Wai Chiu1, Queenie Chan2, Henry Ka Fung Mak

1Diagnostic Radiology, The University of Hong Kong, HK, Hong Kong; 2Philips Healthcare, Hong Kong

T1 and T2 relaxation time values vary in different regions and magnetic environments. Though T1 and T2 correction factors are necessary in absolute quantification, previous MRS studies mainly obtained the values from literature since the measurements require much time to be conducted. In this 1H-MRS study of aging, T1 and T2 values were measured within the sampling population in order to achieve higher accuracy at 3-Tesla. This study demonstrated the measurements only take reasonable amount of time with our method employed.