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Abstract #1018

3D MR Imaging of Intraplaque Hemorrhage (MRIPH) & 3D TOF MRA at 3T for Atherosclerotic Arterial Wall Evaluation: a Comparison with 2D Multi-Contrast MRI

James Qiupeng Zhan1, Alan Moody1, 2, Cristina Nasui3, Herve Jeufack1

1Sunnybrook Hospital, Toronto, Ontario, Canada; 2Medical Imaging,, University of Toronto, Toronto, Ontario, Canada; 3Medical Imaging, University of Toronto, Toronto, Ontario, Canada


To assess whether 3D MRIPH and 3D TOF MRA at 3T could be used for arterial wall evaluation independent of 2D multi-contrast MRI sequences. 10 patients were scanned and acquired 3D High-Spatial-Resolution MRIPH, 3D TOF, and 2D multi-contrast MRI. Lumen boundary on 3D TOF and outer wall boundary on 3D MRIPH were segmented, as well as on the 2D multi-contrast images. There is very close agreement between 3D MRIPH combined with 3D TOF MRA when compared to the 2D multi-contrast MRI. This methods give a thorough description of atherosclerotic vessel wall disease. It potentially overcomes some problems of prolonged scan time and registration of images from multiparametric 2D data sets.