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Abstract #1026

Measurement of Perfusion During Transient Carotid Occlusion

Matthew Ethan MacDonald1, 2, Parviz Dolati, 23, Linda Andersen, 23, Cheryl R. McCreary, 23, John Wong, 23, Richard Frayne, 23

1Biomedical Engineering, University of Calgary, Calgary, AB, Canada; 2Seaman Family MR Research Centre, Foothills Medical Centre, Alberta Health Services, Calgary, AB, Canada; 3Radiology and Clinical Neurosciences, University of Calgary, Calgary, AB, Canada

In this work we demonstrate the measurement of cerebral perfusion rapidly during neurovascular intervention with arterial spin labeling. A canine model for transient carotid vessel occlusion using endovascular devices is explained. Measures of different vascular territories are performed during carotid vessel occlusion. The temporal course of perfusion is evaluated during the stroke. Collateral flow is shown to sufficiently supply blood to the cortical regions, but flow is detectably lower in white matter during the stroke.