Abstract #1035

Evaluation of a New QBOLD Approach to Map Local Blood Oxygen Saturation in Arteriovenous Malformation Patients

Julien Bouvier¹,², Florence Tahon³, Irne Troprs⁴, Omer Eker³, David Chechin², Jean-Franois Le Bas,³⁴, Alexandre Krainik³,⁵, Emmanuel Luc Barbier¹,⁵

¹INSERM U836, Grenoble, Isre, France; ²Philips Healthcare, Suresnes, Ile de France, France; ³CHU, Grenoble, France; ⁴3T Facility, SFR Biomedical NMR and Neurosciences, Grenoble, France; ⁵Universit Joseph Fourier, Grenoble Institute of Neurosciences, Grenoble, France

Quantitative Blood Oxygen Level Dependent allows quantitative evaluation of cerebral tissue hemodynamic parameters, such as the blood volume (BVf), deoxyhemoglobin concentration or local oxygen saturation (lSO2). An approach that combines separate estimates of T2, T2*, BVf and B0 inhomogeneities has recently been proposed and validated in rats. The aim of this study is to evaluate this approach in patients bearing an arteriovenous malformation (AVM) and evaluate the oxygenation status in the tissue surrounding the AVM nidus.