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Abstract #1035

Evaluation of a New QBOLD Approach to Map Local Blood Oxygen Saturation in Arteriovenous Malformation Patients

MAGNA25Julien Bouvier1, 2, Florence Tahon3, Irne Troprs4, Omer Eker3, David Chechin2, Jean-Franois Le Bas, 34, Alexandre Krainik3, 5, Emmanuel Luc Barbier1, 5

1INSERM U836, Grenoble, Isre, France; 2Philips Healthcare, Suresnes, Ile de France, France; 3CHU, Grenoble, France; 43T Facility, SFR Biomedical NMR and Neurosciences, Grenoble, France; 5Universit Joseph Fourier, Grenoble Institute of Neurosciences, Grenoble, France

Quantitative Blood Oxygen Level Dependent allows quantitative evaluation of cerebral tissue hemodynamic parameters, such as the blood volume (BVf), deoxyhemoglobin concentration or local oxygen saturation (lSO2). An approach that combines separate estimates of T2, T2*, BVf and B0 inhomogeneities has recently been proposed and validated in rats. The aim of this study is to evaluate this approach in patients bearing an arteriovenous malformation (AVM) and evaluate the oxygenation status in the tissue surrounding the AVM nidus.