Yi Zhang1, Oscar San Emeterio Nateras1, Qi Peng1, Joseph M. Harrison2, Timothy Duong1, 3
1Radiology, University of Texas Health Science Center at San Antonio, San Antonio, TX, United States; 2Ophthalmology, University of Texas Health Science Center at San Antonio, San Antonio, TX, United States; 3Ophthalmology , University of Texas Health Science Center at San Antonio, San Antonio, TX, United States
MRI of the human retina is challenging due to its thin structure requires high spatial resolution, and eye movement in unanesthetized humans may cause considerable motion artifacts. This study first demonstrated the adequate eye fixation stability using cued blinks as evaluated by an independent eye tracker. It also reported the feasibility of using high-resolution MRI to delineate the laminar structure of the human retina at 3T. MRI layer assignments were corroborated by using contrast-enhanced MRI which selectively enhanced the vascularized boundaries of the retina. This study encourages further investigation of depth-resolved retinal MRI and its applications in retinal diseases.
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