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Abstract #1130

Highly Accelerated Cine-MRI in Mouse Hearts Using Compressed Sensing and Parallel Imaging at 9.4T

Tobias Wech1, Victoria Thornton2, Craig A. Lygate2, Stefan Neubauer2, Herbert Kstler1, Jrgen E. Schneider2

1Institute of Radiology, University of Wrzburg, Wrzburg, Germany; 2Cardiovascular Medicine, University of Oxford, Oxford, United Kingdom

Parallel Imaging (PI) and Compressed Sensing (CS) have been shown to individually provide a three-fold reduction in scan-time for cine MRI in mice whilst providing accurate measurement of the physiologically relevant parameters. We now sought to combine PI and CS to further accelerate cine-MRI in mouse hearts at 9.4T. Fully acquired cine-data sets were retrospectively undersampled (overall acceleration factors combined: 4 up to 16) and subjected to CS and PI reconstruction, followed by image analysis. It is shown that a 3x3-fold acceleration (RCS x RPI) still allows for accurate assessment of cardiac functional values.