Highly Accelerated Cine-MRI in Mouse Hearts Using Compressed Sensing and Parallel Imaging at 9.4T

Tobias Wech¹, Victoria Thornton², Craig A. Lygate², Stefan Neubauer², Herbert Kstler¹, Jrgen E. Schneider²

Parallel Imaging (PI) and Compressed Sensing (CS) have been shown to individually provide a three-fold reduction in scan-time for cine MRI in mice whilst providing accurate measurement of the physiologically relevant parameters. We now sought to combine PI and CS to further accelerate cine-MRI in mouse hearts at 9.4T. Fully acquired cine-data sets were retrospectively undersampled (overall acceleration factors combined: 4 up to 16) and subjected to CS and PI reconstruction, followed by image analysis. It is shown that a 3x3-fold acceleration (RCS x RPI) still allows for accurate assessment of cardiac functional values.