Improved Temporal Resolution of Dynamic Oximetry Via Keyhole Acquisition for Quantifying Reactive Hyperemia

Michael C. Langham¹, Felix W. Wehrli¹

The current temporal resolution of dynamic oximetry is limited to 5s and thus may not be able to resolve potentially important information that could differentiate subtle differences in the vascular reactivity. Reducing TR is not a satisfactory solution since it will lead to unacceptable SNR in reference tissue as well as a minor loss of blood signal due to saturation effect. In this work we implemented and evaluated the keyhole acquisition scheme for improving the temporal resolution of dynamic oximetry by a factor of four without sacrificing SNR and accuracy.