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Abstract #1163

Fast Simultaneous Non-Contrast Angiography and Intra-Plaque Hemorrhage (FSNAP) Imaging for Atherosclerotic Disease with Low-Resolution Reference Scan and Corrected Phase Sensitive Reconstruction

Huijun Chen1, Jinnan Wang2, Xihai Zhao3, Chun Yuan1, William S. Kerwin1

1University of Washington, Seattle, WA, United States; 2Philips Research North America, United States; 3Department of Biomedical Engineering, Tshinghua University, Beijing, China

SNAP sequence has been proposed to image both the luminal stenosis and intraplaque hemorrhage in atherosclerosis patient in one scan. In SNAP, the blood signal presents only negative signal that can be used to generate non-contrast MRA, while all other tissues presents T1-weighted positive signal, providing a good hemorrhage detection tool. However, the phase-sensitive reconstruction in the SNAP sequence requires a full-resolution reference scan, which doubles the scan time. In this study, we propose a fast SNAP (fSNAP) sequence with low resolution reference scan and a corrected phase-sensitive reconstruction to speed up the acquisition without compromising the image quality.