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Abstract #1176

A Novel 4D Flow Tool for Comprehensive Blood Flow Analysis

Mehmet A. Gulsun1, Marie-Pierre Jolly1, Jens Guehring2, Christoph Guetter1, Arne Littmann2, Andreas Greiser2, Michael Markl3, Aurelien F. Stalder2

1Image Analytics and Informatics, Siemens Corporate Research, Princeton, NJ, United States; 2Siemens AG Healthcare Sector, Erlangen, Germany; 3Northwestern University, Chicago, IL, United States

4D Phase Contrast (PC)-MRI is gaining attention for assessing blood flow. Therefore the accuracy and reproducibility of this process becomes critical. We present a comprehensive 4DFlow software package for advanced flow quantification and visualization. This software integrates background phase and velocity aliasing corrections, 4D vascular centerline and lumen segmentation, automated quantification and 3D visualization. Five cases were evaluated giving inter-method and inter-observer errors within 10% of the measured dimension. Results demonstrate that an integrated 4D flow post-processing approach can reduce processing times to a few minutes while enhancing accuracy and objectivity and thus help bring the technique to the clinic.