Marijn P. Rolf1, Mark BM Hofman1, Joost PA Kuijer1, Rob J. van der Geest2, Aernout M. Beek3, Albert C. van Rossum3, Rudolf M. Verdaasdonk1
1Physics and Medical Technology, ICaR-VU, VU University Medical Center, Amsterdam, Netherlands; 2Radiology, Leiden University Medical Center, Leiden, Netherlands; 3Cardiology, ICaR-VU, VU University Medical Center, Amsterdam, Netherlands
The feasibility of a new 7D PC-SSFP sequence for mitral regurgitation volume quantification is assessed. The 7D PC-SSFP sequence implementation is based on a balanced SSFP gradient scheme with velocity encoding. Mitral volume flow was determined in ten healthy subjects and in two patients with mitral insufficiency. It was measured directly at the mitral valve using 7D PC-GE and 7D PC-SSFP, and indirectly using aorta flow and left ventricular volumes. Images showed reasonable quality, although occasional respiratory motion artifacts were noted. Regurgitation volumes in healthy subjects were not significantly different from zero and a clear regurgitation was observed in both patients.
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