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Abstract #1209

Evaluation of Non-Contrast Dynamic MRA in Intracranial Arteriovenous Malformation (AVM): Comparison with Time of Flight (TOF) and Digital Subtraction Angiography (DSA)

Songlin Yu1, Lirong Yan2, Yuqiang Yao3, Shuo Wang, Mingqi Yang, Bo Wang4, Yan Zhuo4, Lin Ai5, Xinyuan Miao4, Jizong Zhao, Danny J. J. Wang2

1 Beijing Tiantan Hospital, Capital Medical University, beijing, China; 2Department of Neurology University of California Los Angeles Ahmanson-Lovelace Brain Mapping Center; 3Beijing Jishuitan Hospital, Peking university; 4The State Key Laboratory of Brain and Cognitive Science, Institute of Biophysics, Chinese Academy of; 5Beijing Neurosurgical institute

Digital subtraction angiography (DSA) remains the gold standard to diagnose intracranial arteriovenous malformations (AVMs) but is invasive. Existing MR angiography (MRA) is suboptimal for assessing the hemodynamics of AVMs. This study evaluated the clinical utility of a novel non-contrast 4D dynamic MRA (dMRA) in the evaluation of intracranial AVMs, through comparison with DSA and time-of-flight (TOF) MRA in 19 AVM patients. DMRA was able to detect 16 out of 19 AVMs, and the ratings of AVM size and location matched those of DSA. The hemodynamic information provided by dMRA improved diagnostic confidence scores by TOF MRA.