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Abstract #1263

4D MRI as the Best Way to Prescribe Patient-Specific Proximal and Distal Boundaries for Numerical Modeling

Vitaliy L. Rayz1, Monica Sigovan1, David Saloner1

1Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA, United States

4D MRI data, providing time-resolved velocity measurements in vivo, can be used to prescribe patient-specific boundary conditions for detailed numerical simulations. This approach connects a computational domain to the proximal and distal circulation, eliminating uncertainties of various modeling assumptions commonly used in the flow modeling practice. We have used 4D MRI to prescribe flow boundaries for computations in a cerebral aneurysm and an arteriovenous fistula and compared these results to computations carried out based on specific different assumptions about the distal circulation. The study demonstrates that boundary conditions based on 4D MRI measurements ensure the accuracy of the numerical simulations.