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Abstract #1305

MR Elastography (MRE): Evaluation of New Inversion Algorithm and Quantitative Analysis Method

Alvin C. Silva1, Annelise M. Silva2, Roger C. Grimm3, Kevin J. Glaser3, Amy K. Hara1, Richard L. Ehman3

1Radiology, Mayo Clinic Arizona, Scottsdale, AZ, United States; 2Xavier, Scottsdale, AZ, United States; 3Radiology, Mayo Clinic Rochester, Rochester, MN, United States

MR Elastography is a promising, noninvasive technique for discriminating normal from diseased liver, including fibrosis stage. With the introduction of a new inversion algorithm (MMDI) and confidence mask, suggested published threshold values in this regard may have to be modified. The purpose of this study is to compare calculated mean shear hepatic stiffness calculations (kPa) between the two inversions algorithms and assess inter- & intraobserver variability between two measurement techniques (ie, confidence threshold mask versus free-hand ROI).