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Abstract #1324

The Feasibility Study of Exploring Arterial Spin Labeling for Renal Glomerular Filtration Rate (GFR) Mapping

Jing Wang1, Yudong Zhang2, Yue Zhang3, Xiaoying Wang, 12, Jue Zhang1, 3, Jing Fang1, 3

1Academy for Advanced Interdisciplinary Studies, Peking University, Beijing, China; 2Department of Radiology, Peking University First Hospital, Beijing, China; 3College of Engineering, Peking University, Beijing, China

This study developed an approach for renal perfusion and glomerular filtration rate mapping based on the combination of pulsed arterial spin labeling technique and a spin-echo EPI with multiple TEs sequence on clinical 3T MR. Each of ten healthy young subjects accepted 12 breath-hold ASL scans for different TEs acquisition. Based on the proposed method, the RBF, blood R2* and GFR maps were obtained simultaneously. We hope that this MR technique can be combined with other functional methods to provide a complete noninvasive assessment of renal status in a single examination.