Meeting Banner
Abstract #1329

DTI in Human Kidney: Image Co-Registration Improves Signal Stability and Lowers Variability in Diffusion Parameter Estimation

Peter Vermathen1, Huanxiang Lu2, Tobias Binser1, Ute Eisenberger3, Chris Boesch1, Mauricio Reyes2

1Depts Clinical Research and Radiology, University Bern, Bern, Switzerland; 2Institute for Surgical Technology and Biomechanics, University Bern, Bern, Switzerland; 3Dept. Nephrology and Hypertension, Inselspital Bern, Bern, Switzerland

Physiological motion caused by respiration leads to image artifacts in abdominal DTI. Even in respiratory triggered scans residual motion remains. The aim of this study on 12 subjects was to employ non-rigid image registration of individual echo planar DTI images of human kidneys, which are virtually free of motion artifacts, and to compare the variability of the determined diffusion parameters and image blurring with the standard processing.