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Abstract #1399

Aging Effect on Zonal and Sex Differences of Human Meniscus Investigated by MR T2 Measurements

Ping-Huei Tsai1, 2, Shih-Wei Chiang3, Yue-Cune Chang4, Chao-Ying Wang3, Ming-Chung Chou5, Hsiao-Wen Chung6, Guo-Shu Huang3

1Imaging Research Center, Taipei Medical University, Taipei, Taiwan; 2Department of Radiology, WanFang Hospital, Taipei, Taiwan; 3Department of Radiology, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan; 4Department of Mathematics, Tamkang University, Taipei, Taiwan; 5Department of Medical Imaging and Radiological Sciences, Kaohsiung Medical University, Kaohsiung, Taiwan; 6Graduate Institute of Biomedical Electronics and Bioinformatics, National Taiwan University, Taipei, Taiwan

Human meniscus plays an important role on maintenance of the knee mechanical functions and is strongly associated with early detection of osteoarthritis (OA) which is frequently characterized with degeneration of cartilage and mostly related to aging. Zonal difference of the meniscus was demonstrated by previous report using quantitative T2 measurements. In addition, aging and gender may be other factors that could affect the diagnostic value of quantitative T2 measurements in the menisci. The purpose of this study is to investigate the relationship between regional T2 variations and aging effect in asymptomatic men and women.