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Abstract #1404

Feasibility of the Residual Red Marrow Assessment in Tibia Epiphysis After Age 25 Using DTI: The Initial Investigation on Healthy Volunteers

Bailiang CHEN1, 2, Tryphon Lambrou3, Gabriela HOSSU1, 4, Pedro Teixeira5, Pierre-Andr VUISSOZ1, 2, Jacques FELBLINGER1, 2

1IADI, INSERM U947, Nancy Universit, Nancy, Lorraine, France; 2Ple Imagerie, CHU de Nancy, Nancy, France; 3Institute of Nuclear Medicine, University College London, London, United Kingdom; 4CIC-IT 801, CHU de Nancy, Nancy, France; 5Service dImagerie Guilloz, CHU de Nancy, Nancy, France

Bone marrow is a dynamic organ with significant changes in its composition throughout life. Alterations in the conversion between red (hematopoietic) and yellow (adipose) marrow may be a sign for an alteration of the local microvascular environment caused by local or systemic diseases. The distribution pattern of red bone marrow, residual or reconverted, may assist the differentiation between normal and pathologic bone marrow. Such residual red marrow is sometimes difficult to be detected by conventional sequences. In this study, we presented an in-vivo diffusion based MR protocol to assess the red marrow in the tibia epiphysis.