Value of Magnetic Resonance Imaging for the Local Staging of Prostate Cancer at 3 T

Josephin Otto¹, Gregor Thrmer¹, Matthias Seiwerts¹, Jochen Fuchs¹, Nikita Garnov¹, Lars-Christian Horn², Harald Busse¹, Thomas Kahn¹, Michael Moche¹

Prostate cancer is characterized by a high incidence but relatively low mortality. Disease prediction, risk stratification and therapeutical decision of histopathologically confirmed prostate cancer are commonly obtained by nomograms, which have a relatively low predictive value. Multiparametric MRI, in contrast, can provide detailed information of unilateral or bilateral extracapsular extension and seminal vesicle invasion, which is important for patients selected for nerve-sparing surgery. The high specificities and relatively high sensitivities observed here suggest that 3 T MRI with an endorectal coil is a suitable diagnostic tool for the local staging of prostate cancer.