Abstract #1518

Evaluation of Melanoma Xenograft Through Chemical Exchange Saturation Transfer Imaging: A Preliminary Report

Mohammad Haris¹, Kavindra Nath², Anup Singh¹, Kejia Cai¹, David S. Nelson², Dennis B. Leeper³, Hari Hariharan¹, Jerry D. Glickson², Ravinder Reddy¹

¹Radiology, University of Pennsylvania, Philadelphia, PA, United States; ²Molecular Imaging Lab, University of Pennsylvania; ³Radiation Oncology, Thomas Jefferson University Hospitals

In this preliminary study, we explored the chemical saturation transfer effect from amino acids particularly glutamate and alanine present in the mouse model of melanoma and image them at high spatial resolution and discuss the potential significance of using this method in the management of human melanoma.