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Abstract #1518

Evaluation of Melanoma Xenograft Through Chemical Exchange Saturation Transfer Imaging: A Preliminary Report

Mohammad Haris1, Kavindra Nath2, Anup Singh1, Kejia Cai1, David S. Nelson2, Dennis B. Leeper3, Hari Hariharan1, Jerry D. Glickson2, Ravinder Reddy1

1Radiology, University of Pennsylvania, Philadelphia, PA, United States; 2Molecular Imaging Lab, University of Pennsylvania; 3Radiation Oncology, Thomas Jefferson University Hospitals

In this preliminary study, we explored the chemical saturation transfer effect from amino acids particularly glutamate and alanine present in the mouse model of melanoma and image them at high spatial resolution and discuss the potential significance of using this method in the management of human melanoma.