DWI Based Thermometry: Analysis Method and Its Applications

Koji Sakai¹, Kei Yamada², Kentaro Akazawa², Naozo Sugimoto

Among MR methods, the most clinically applicable assessing-the-brain-temperature method could be the post processing of the DWI. Although only applicable to the non-restricted water, it is thought to be potentially useful in assessing the thermal pathophysiology of the brain. The purpose of this study was to develop new calculation method, which does not require user depending threshold. The mean ventricular temperature of 23 healthy subjects (aged 26-75 years) were calculated by four methods: two thresholding methods and two histogram curve-fitting methods. The histogram curve-fitting methods seemed to yield more appropriate temperatures, using tympanic temperature as a reference.