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Abstract #1650

Study on the Single Cell Detectability as the Concentration of Contrast Agent

Jee-Hyun Cho1, 2, Janggeun Cho1, 3, Sangdoo Ahn3, Chulhyun Lee1

1Magnetic Resonance Research, Korea Basic Science Institute, Ochang, Cheongwon, Korea, Republic of; 2Chemistry, Chung-Ang University, Seoul , Korea, Republic of; 3Chemistry, Chung-Ang University, Seoul, Korea, Republic of

In this study, to numerically evaluate how to change the detectability and image-contrast depending upon the concentration of contrast agents, we systematically compared the fractional signal losses of iDQC, EPI, and GE images of single cells labeled with different iron concentrations. The iDQC images visualized labeled cells more effectively and with a higher contrast-to-noise ratio than conventional EPI and GE images, especially at low resolutions and low iron concentration in cell.