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Abstract #1673

A Low Field Dual Channel Heteronuclear RF Probe for Hyperpolarized Magnetic Resonance Imaging at 0.0475 T

Aaron M. Coffey1, 2, Roman V. Shchepin1, Ken Wilkens1, Kevin W. Waddell1, Eduard Y. Chekmenev1

1Vanderbilt University Institute of Imaging Science, Vanderbilt University, Nashville, TN, United States; 2Biomedical Engineering, Vanderbilt University, Nashville, TN, United States

A low field MR imaging system for heteronuclear hyperpolarized contrast agents in vivo is under development to demonstrate utility for human scale. Hyperpolarization reopens examination of low field imaging leveraging multi-turn inductors. A 206 turn 13C single layer solenoid coil was used to polarize by PASADENA and detect in situ hyperpolarized 1-13C-succinate-d2 (P = 15%, 13C SNR = 500, FWHM = 22 Hz). Comparison with identical phantom and polarization yielded SNR = 120 with FWHM = 6 Hz for a Doty volume coil (4.7 T) with the solenoid coil (0.0475 T) yielding SNR = 30 with FWHM = 25 Hz.