Abstract #1715

JAM-PRESS: Improving the Resolution of J-Resolved PRESS with Editing Pulses

Richard AE Edden¹,², Nicolaas AJ Puts¹,², Peter B. Barker¹,²

¹Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins University, Baltimore, MD, United States; ²FM Kirby Center for Functional Brain Imaging, Kennedy Krieger Institute, Baltimore, MD, United States

In this abstract, we introduce a new experiment JAM-PRESS that combines the resolution benefits of J-resolved and Mega-edited PRESS measurements. This is achieved by adding editing pulses to alternate TE increments of a J-PRESS experiment. Essentially this modification separates edited and unedited peaks by half the F1 spectral width, improving the resolution of the editing target while retaining J-resolution for other maetabolite peaks. The method is demonstrated in phantom and in vivo as applied to GABA.